Sentence examples for mutations or gene from inspiring English sources

Gene mutations or gene amplifications in tumor cells that influence the uptake, metabolism, or export of drugs were considered the main reasons for chemotherapy resistance.

Mutations or gene amplification are found in components of the PI3K/Akt pathway in a large number of tumors [34].

Certain signaling pathways involved by such mutations or gene amplifications, outlined below, have key roles in regulating mechanisms that lead to the adaptation of the Warburg effect as the metabolic hallmark of cancer cells.

The transient MFA technique can be used to measure and compare fluxes under different conditions of light intensity, nitrogen sources or compare strains with various mutations or gene deletions and additions.

We analyzed data for 112 patients treated with platinum-based first-line chemotherapy at our center between October 2011 and March 2017 and who were screened for the presence of FGFR mutations or gene fusions within multiple clinical trials with pan-FGFR inhibitors.

This can be conferred by point mutations or gene amplification events.

Mutations or gene-deletions of several nuage components in mammals and arthropods result in male sterility and genomic disruption due to uncontrolled transposase activity [ 3, 5].

For either targeted mutations or gene-trapped mutations, transfected mESC clones can be selected after screening for disrupted alleles in the gene of interest.

We will also consider more complex genetics including genes with a combination of de novo and rare inherited mutations or genes with only rare inherited mutations.

Current technology allows gene expression to be down-regulated using antisense or co-suppression and future developments may allow targeted gene mutation or gene replacement.

These data also suggest that the initiation of epithelial-derived tumors as a result of APC mutation or gene silencing may be driven by loss of polarity and dysmorphogenesis.