Sentence examples for mutations on interferon from inspiring English sources

Using transient transfection reporter assays, we investigated potential effects of the promoter mutations on interferon responsiveness.

We showed that the selection of such cavity mutations in interferon- γ receptor 1 (IFN γR1) could be performed based on a combination of simple empirical force-field calculations and MD simulations.

Mr. Milstein also supported research on interferon, the hepatitis and cancer drug.

Trials on interferon or pegylated interferon alone or with ribavirin were eligible for inclusion.

The only effective treatment is based on interferon alpha (IFN-α).

Classical therapy based on interferon provided low rates of HCV cure in the HIV setting.

She received prednisolone treatment and was started on interferon β therapy.

He also reported on work by Newport and co-workers [ 2] and Jouanguy and co-workers [ 3] showing that mutations in the interferon (IFN γ receptor 1 gene increased susceptibility to microbacterial infection.

Evidence indicates that certain IRF-5 mutations, by regulating interferon type I activity, confer susceptibility to SLE [ 36, 37].

Using KEGG to map genes to pathways (see Additional file 3) [ 50], mutations in three interferon receptor genes IFNA14, IFNW1, and IFNA17 belong to multiple pathways that have significant impact on cancer, including the Cytokine-Cytokine receptor pathway and the JAK/STAT pathway.

(1) Chemical mutagenesis followed by selection of small plaques mutants in the presence of interferon; (2) Selection on interferon-deficient cells in order to relieve the pressure to keep interferon resistance.