Sentence examples for mutations of the two from inspiring English sources

Mutations of the two Cys residues can significantly impair the binding ability of hCutC with Cu(I).

Somatic mutations of the two genes coding for the histone acetyltransferase genes, CREEBP and EP300 have been identified as a pathogenetic mechanism shared by common forms of B-cell non-Hodgkińs lymphomas.

Mutations of the two AP-2α binding sites in the PP2A-Aα promoter abolished this dose-dependent response (data not shown).

As shown in Figure 3B, FBS and WY-14643 efficiently induced CYP1A1 promoter transactivation (2.5-fold) while the mutation of one PPRE site alone slightly reduced luciferase activity, and the mutations of the two PPRE sites abrogated it.

There is so far no evidence to show that these enzymes are essential: single and double knock-out mutations of the two genes that code these glycosylase enzymes in Arabidopsis thaliana do not increase the sensitivity of the plants to oxidative stresses or reduce the viability of seed [4].

However, no mutations of the two genes, analyzed for the first time in gynecological melanomas, were detected in our series.

For example, mutations of the four positively charged residues, R1639G, R1642S, R1645Q, and R1648C, are present in the domain IV S4 segment (Table 2), suggesting that these EIEE6 mutations may alter the voltage sensing behavior of the channel.

Nonetheless, simultaneous mutations of the three LRR-RKs genes (pxy-3 with pxl1 and pxl2) generated an enhanced vascular phenotype observed in pxy-3 plants with flatter vascular bundles and a less clear distinction between xylem and phloem.

In contrast, mutations of the miR-128 and 27a/b binding nucleotides 14 and 236 of the 3'-UTR relieved the miR-mediated repression of luciferase activity.

To further characterize the function of the base excision repair pathway in plants, we have located and combined insertion mutations of the three abasic endonuclease genes.

This fragment was replaced with a synthesized fragment that contained mutations of the four consensus sites at T386, S416, S441, and S447 to alanines (pTE13).