Sentence examples for mutations of small from inspiring English sources

In addition, these authors reported cases where the distribution of mutational effects changed from many divergent loci with mutations of small effect to few loci with mutations of large effect.

It has revealed lots of mutations of small effect.

This paper also discusses some of the open questions, such as how much more common beneficial mutations of small effect are than those of large effect.

In other words, although mutations of small effect are more common, the actual establishment of adaptive changes will often be due to mutations of medium to large effect, especially on arrival in a tough new place.

Instead, the pattern of inheritance suggests that many mutations of small individual effect come together to produce a risk rather than a certainty.GWAS has not been a total failure.

Interestingly, genetic mutations of small heat shock proteins are found in diseases involving neurons, muscular tissues and ocular lens that arise from defects in protein folding.

Point mutations totalled 756 (10% of all mutations, 52% of small mutations) with 726 nonsense mutations (10% of all mutations, 50% of small mutations) and three missense mutations (<1% of all mutations, 2% of small mutations).

MA experiments maintain lines under extremely low effective population size to minimize the effects of selection, reducing its efficacy so that mutations of small-to-moderate effect accumulate at a rate approximately equal to their occurrence (Lynch et al. 1999).

Although, there are workflows to evaluate ligand-binding energetics which require significant computational time and setup through free-energy calculations involving Molecular Mechanics/Generalized Born Surface Area method (MM-GBSA), there is however, no intuitive web-tool available for analyzing alanine-scanning mutations of small-molecule binding site residues in real time.

These null mutations are unlikely to be representative of naturally occurring mutations of smaller effect (Stern 2000).

Highly advantageous mutations have a higher probability of escaping loss by genetic drift and are also expected to reach high frequency more rapidly than mutations of smaller beneficial effect [ 2].