Sentence examples for mutations of several from inspiring English sources

Mutations of several residues include the highly conserved Asp1343.32, which is known to cause 5-HT1B or 5-HT2B receptors to abolish the monoamine ligand binding as reported in the literature (Wang et al. 2013).

Epigenetic silencing and point mutations of several genes are commonly found in Type I endometrial cancer.

The conditions are caused by genetic mutations of several different genes including, VPS13A, XK, JPH3 and PANK2.

Furthermore, mutations of several cullin genes have been identified in human growth retardation syndromes.

Indeed, mutations of several cytoskeletal proteins have been subsequently found in patients with familial FSGS [ 10].

In humans, mutations of several genes involved in DDR have been associated with premature aging syndromes (Jackson and Bartek, 2009).

The initial CDR-grafted antibodies tend to lose the parental binding affinity, and therefore require additional work for back-mutation of several murine framework amino acids, which are regarded to be crucial for CDRs loop conformation [10].

Mutation of several genes in a regulatory pathway may be functionally equivalent.

Furthermore, mutation of several triplets of amino acids (525NTI, 529EKV, and 533IMI) between N525 and I535 abrogated ANO6 PLS activity.

Mutation of several residues in the N-terminal region, especially N8A and L14A, also caused an elevation in substrate cleavage.

For example, heterozygous mutation of several genes belonging to the same or different pathways could lead to phenotypic heterogeneity.