Yeast strains containing the mutations of non-consensus sites (as described in Table 2) were constructed as follows.
Furthermore, we identified four dominant mutations of non-signature residues in NA, HA, and NS1 proteins of the 2009 H1N1pdm virus.
Thus, mutations of non-Watson−Crick interaction in either SRL motif were avoided to prevent unpredictable perturbations to the RNA structure.
Although experts have dismissed the relevance of changes related to polymorphic mutations of non-B subtypes, low-to-moderate resistance to HIV drugs has been reported in neighboring central African countries in which high HIV diversity was found [ 28, 29].
The MJ Network also shows that the mutated alleles P272 (Chardonnay musqué 44-60 Dijon), C306 (Gewürztraminer and Siegerrebe) and del GVTKQ 285-289 (Chasselas musqué) arose independently from single mutations of non-aromatic Chardonnay 130 and Chasselas haplotypes.
The genetic bases of apple russeting is supported by such evidences as (i) apple collections with cultivars that display considerable russeting variability, irrespective of growth conditions; (ii) the occurrence of russeted sport mutations of non-russeted cultivars, and (iii) the segregation of the character in controlled crosses.
Further, possible effect of BRCA mutations on non-cancer mortality risk has not been examined.
A set of 13 waxy rice genotypes prepared by chemically-induced mutation of non-waxy rice variety TNG67 and 7 waxy rice varieties widely planted in Taiwan were screened for various structural and gelatinization properties of starches.
R120W is considered as the third most common mutation of non-neuropathic GD.
Indirect resistance, such as mutation of non-targeted sites within the viral promoter, can lead to upregulation of viral transcription, thereby allowing viral escape by overwhelming the RNAi-mediated selective pressure [ 106, 107].
Mutation of non-canonical residues back to the canonical residues for atypical Arf/Arl GTPases could also be informative (and seem unlikely to introduce dramatic structural perturbations given their prevalence within typical Arf/Arl GTPases).
