Sentence examples for mutations of intermediate from inspiring English sources

"Mutations of intermediate effect are responsible for adaptation in evolving Pseudomonas fluorescens populations".

Knowing g ¯ and the mutation rate allows us to directly calculate the fate of neutral or very unfit mutations, but estimating the frequency of mutations of intermediate fitness requires additional simulations using our model.

To reduce evolution in this space to a manageable form, one can construct shortest paths from sequence A to sequence B that involve minimum numbers of mutations of intermediate strains.

In contrast, Fisher's geometric model and subsequent work from other researchers has shown that mutations of large effect are less likely to be lost due to drift than small-effect mutations, and thus, on average, we should predict mutations of intermediate effect during an adaptive walk [ 8].

Because the number of stages and the mutation rates of intermediate cells in different pathways are different and different drugs may affect different pathways, we believe that this is important and necessary.

The GF1B locus also displayed a clear excess of mutations with an intermediate average frequency which correspond to the substitutions of the internal branch in Figure 10.

People affected by mutations that occur at very flexible sites should possess a relatively high residual activity and are likely to develop a mild and late form of the disease, people affected by mutations occurring at sites of intermediate flexibility should possess some residual activity and are likely to develop a mild form of the disease that is responsive to pharmacological chaperones [23].

Logically, the CO1 and SAHH loci showed an excess of mutations with an intermediate average frequency which are indeed the fixed differences between the two species.

To obtain evidence of a recent selective sweep, we used Fay and Wu's H test, which measures an excess of derived high-frequency mutations to intermediate-frequency mutations.

Mutations of cytoplasmic dynein light intermediate chain 2 (Dync1li2) and dynein intermediate chain (Dync1i) result in reduction of dendrite arborization of Drosophila neurons (Zheng et al., 2008; Boylan and Hays, 2002).

Substitutions that were fixed during allopatry would then be dispatched among chromosomes by recombination but if introgression was balanced enough and the number of substitutions was high enough, an excess of mutations in intermediate frequency should be observed.