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Mutations of either of N106R or L112R inhibited PML RING tetramerization (Fig. 3f).
Mutations of either XLF or XRCC4 that ablated their interaction disrupted pull-down of the 500 bp fragment.
Serine-to-alanine mutations of either S142, S138, or S211 induce constitutive nuclear localization and activity of TFEB3,17,18,19,21.
Thirteen of 21 (62%) tumors were found to have mis-sense mutations of either TP53 or RAS.
Mutations of either Aurora or Polo were shown to cause symmetric cell division by disturbing the asymmetric localization of fate determinants such as aPKC, Numb, Pon, and Notch.
Mutations of either of these two sites considerably reduced luciferase repression by let-7c.
Similar(16)
Mutation of either lysine to alanine makes it less likely for a carbamate to form at the other site.
Germ-line mutation of either TSC gene leads to the development of the heritable disorder TSC.
Of the five individuals, four were found to have somatic EPAS1 mutations, all of which resulted in mutation of either amino acid residue A530 or P531 (P531R (x2), P531R, A530P 45.
Mutation of either one or both tyrosine residues to histidine conferred hydrolytic activity on previously inactive antibody 3F4.
Furthermore, we demonstrate that the mutation of either T242 P or U7-U8 compensatesathetheffectcausedsed by the mutation of R7A on the replication of rVSVR7A.
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