Sentence examples for mutations of any from inspiring English sources

Consistent with the structural model, mutations of any of the hydrophobic residues on ATRX destabilized the DAXXDHB-ATRXDBM interaction (Fig. 2B).

All eight conserved His residues are essential for stearoyl-CoA desaturase activity, as mutations of any of these residues abrogate enzymatic activity [13].

Mosaicism can involve multicellular clonality for mutations of any size (3, 4).

However, reporter activity modulations occurred following mutations of any binding site which indicates that they are all functional.

It does decline under MA, as expected if it is a fitness component, but it also shows the highest number of lines with beneficial mutations of any trait.

In some cases SDHBIHC- is due to germline and/or de novo mutations of any of the four SDH subunits (SDHAmut) [ 6– 8].

In their study, sequential mutational analysis revealed that FOXL2 binding was reduced by mutation of any of the 12 consecutive base pairs at their site.

Mutation of any of these tryptophans disrupts the architecture of the active site.

Mutation of any of its components results in loss of cell-cell adhesion, thereby contributing to malignancy.

Thus, mutation of any single gene may cause a genomic imbalance, with consequences sufficient to drive adaptive genetic changes.

Mutation of any of these five residues influences receptor binding; for example, mutations to E148, which abolished binding to VD1, impaired the interaction with VEGFR-2 but enhanced binding to VEGFR-3.