Sentence examples for mutations of an from inspiring English sources

The best known is hemophilia, caused by mutations of an X-linked gene.

Mutations of an active site glutamate to either aspartate or alanine drastically increase the Km for homoserine, assigning this glutamate to a binding role for the α-amino group of homoserine.

The possible modifying effect on MBC risk in subjects carrying BRCA1/2 germ-line mutations of an occupation characterised by exposure to chemicals such as polycyclic aromatic hydrocarbons (PAH) that are capable of inducing DNA damage, may provide clues to the role of environmental exposures in modifying BC risk in mutation carriers in both genders.

Such receptors comprise fast evolving proteins that are coupled to signal cascades and are capable of adapting to new or changing environmental cues in a relatively short period of time through slight mutations of an ancestor receptor [43].

There are two X-linked sideroblastic anemias (XLSAs), one caused by mutations of an erythroid-specific form of the heme biosynthetic enzyme aminolevulinic acid-synthase (ALAS2) [6], and one caused by mutation of a mitochondria-localized transport protein, ATP-binding cassette, member b7 (ABCb7) [7]—that plays a role in maturation/transport of iron-sulfur cluster containing proteins.

This difference suggests that each of these three groups may have been formed by relatively recent, independent mutations of an ancestral C+ form.

Researchers hope it will directly combat the most common mutations of a protein that malfunctions in cystic fibrosis patients.

Leach, F. S. et al. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer.

Leach, F.S. et al. Mutations of a mutS homolog in hereditary non-polyposis colorectal cancer.

But the study does suggest that tumor samples from a single metastasis typically represent the full set of functional driver mutations of a patient's cancer.

This technique has been shown to be powerful in combining independently isolated mutations of a gene into a single progeny.