Exact(2)
CDH1 gene mutations occurred frequently in hereditary diffuse gastric cancer (HDGC) [ 4, 5].
CIC and FUBP1 mutations occurred frequently in ODs (46% and 24%, respectively) but rarely in astrocytomas or oligoastrocytomas (<10%).
Similar(58)
KRAS and BRAF, two key molecules of the MAPKinase pathway, are frequently mutated in sporadic MSI gastrointestinal cancer, and KRAS mutations occur frequently in HNPCCs (3, 5).
Killela, P. J. et al. TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal.
In lung cancer, KRAS mutations occur frequently at codons 12 and 13 and less frequently at codon 61 [10].
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal.
IDH1/2 mutations occur frequently in low-grade glioma and secondary glioblastoma (~80%), but can also occur in acute myeloid leukemia (20%), angioimmunoblastic T-cell lymphomas (20%), and rarely in other malignancies such as thyroid, colorectal, and prostate cancer (Table 1) (Kang et al., 2009; Yen et al., 2010; Ghiam et al., 2012; Ohgaki and Kleihues, 2013; Yen et al., 2017).
We found that within hosts, proteasome and TAP escape mutations occur frequently.
Both types of mutations occur frequently in HIV, particularly in poorly conserved regions, such as HIV gag.
Such a library would correctly identify more sequence variants than a traditional tiling library with variation at the single position where multiple mutations occur frequently within single probes and those mutations reflect a limited set of possible variants.
RAS mutations occur frequently in human cancer and activated RAS signalling contributes to tumour development and progression.
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