Sentence examples for mutations observed indeed from inspiring English sources

When technology was developed such that comprehensive sequencing of genes across the entire genome became feasible; the pattern of mutations observed indeed fitted this model.

We therefore conclude that the SNP mutations observed do indeed represent the neutral rate.

A similarly high prevalence of non-hotspot ESR1 mutations were identified in a recent plasma ctDNA NGS study of ER + MBC, whereas they were not identified in ER negative cancer patients.10 Further research is necessary to determine if these non-canonical ESR1 mutations observed in plasma ctDNA are indeed tumor-derived and if they have any impact on therapeutic sensitivity.

It is an open question whether these two adaptive trajectories or indeed, the >1200 mutations observed during the experiment lead to convergent phenotypes beyond an increased ability to grow at 42.2 °C.

The complementation of the lrx3 lrx4 double mutant with LRX3 and LRX4 combined with the analysis of the double/triple mutants provide good evidence that the mutant phenotypes observed are indeed caused by the mutations in these three LRX genes.

Acquired drug-resistance mutations were indeed observed in all plasma samples sequenced after failure (data not shown).

A significantly higher number of G mutations was indeed observed in the WRC or GYW motifs in NBS patients (Fig. 2 and Table 2), whereas G residues outside these motifs were targeted equally (11.3% vs. 11.1% of total mutations in controls).

Such mutations are indeed observed in several types of human cancer including melanoma.

In the unique previous study on this issue, no BRAF mutation was indeed observed in a small subset of human HCC patients.

The functional mutS allele of Z2491 was then introduced into Z5463 as described in the experimental procedure section, which reverse this hypermutator phenotype (Fig. 3B), demonstrating that the high mutation rate observed with Z5463 was indeed due to the defective mutS allele.

Indeed, only point mutations were observed to have accumulated in the epithelial mucosa while the considerably smaller number of mutations accumulated in the serosa were, at least in part, genome rearrangements.