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Mutations not only arise in proliferating cells but also in resting - thus non-replicating - cells.
The introduced mutations not only lead to an improved capability to reduce progesterone but also to altered substrate preference.
These mutations not only successfully abrogate the intended ASM, but also do not significantly affect the integrity of the other ASMs (Supplementary Figs. 7, 8a).
In this method, it is possible to discriminate the mutations, not only frequently used positions 261 and 796 but also position 703 in a single PCR.
In contrast to viruses, drugs and chemicals have been shown to cause mutations not only in human cells in culture but also in a living host.
The survival advantage was so powerful perhaps because those with the mutations not only gained extra energy from lactose but also, in drought conditions, would have benefited from the water in milk.
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The mutation not only made tomatoes turn uniformly green and then red, but also disabled genes involved in ripening.
A rad52− mutation not only blocked the appearance of survivors, but in addition, an est1-Δ rad52-Δ strain also displayed a greatly accelerated senescence phenotype (Lundblad and Blackburn, 1993).
She then inserted that mutation into mice genomes.The effect was clear: the animals with the mutation not only began to sleep less than their counterparts but continued functioning well even after six hours of sleep deprivation (a long time for a mouse).
This refers to the extinction or mutation not only of the old bulge-bracket firms but also of the caste that has found haven and easy riches there, the hundreds of thousands of workers, many of them neither extraordinarily skilled or highly trained, who perhaps mistook the fruitions of cheap credit for proof of their own acumen and flair.
The R525H mutation not only causes a defect in pre-rRNA processing but also inhibits cell cycle progression through the MDM2-RB-E2F axis (Kadono et al., 2016).
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