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At variance, the −1T, +1A and +2C 5′ss mutations, not corrected by loading the U1 snRNA directly on the donor site (Fig. 2A), were also not influenced by ExSpeU1 Fig9 (Fig. 6A, lanes 11 16).
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Random mutations occur in the RNA genome when reverse transcriptase converts the RNA into DNA; these mutations are not corrected and are passed on in subsequent replication cycles.
This was unexpected and suggests that mutations that are not corrected by mismatch repair are an important source of the genetic differences found between different humans, and between humans and their ancestors.
His records were not corrected.
Complexity is not corrected.
Not corrected for ties.
(The small difference between the two inferred best GC contents is likely due to difference in the GC content of the second bases of codons, because our model does not correct for mutations at these bases).
Therefore, we included this variable as a factor (with studies where we extracted the information on mutation rate directly from the publication being scored as 0, and studies where we estimated mutation rate after exclusion of extra-pair parentage were scored as 1) in the analyses because we could not correct all mutation rate estimates due to missing values.
Soares et al. (2009), however, did not correct for multiple mutation hits and, in addition, the distance was erroneously underestimated (Pedro Soares, personal communication).
Although co-overexpression of GroESL can assist to overcome protein misfolding in terms of aggregation and by this promote the formation of correctly assembled oligomers (29), it does not correct for the mutation induced structural defects of the variant protein.
"Not correct.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com