Sentence examples for mutations none of from inspiring English sources

Three of the 21 patients carried one or two insertion or deletion mutations, none of which was detected by the microarray.

Although we found several mutations, none of these were considered pathogenic.

In contrast to women with heterozygous BRCA1 germline mutations, none of the heterozygous Brca1 mouse mutants developed spontaneous mammary tumours.

For patient #3, a PCR product was obtained from the D0 sample, in which we identified five mutations none of which affected the gyrA codons 83 or 87.

As observed for H-ras switch III mutations, none of the three N-ras mutations altered the subcellular distribution of N-ras.

The most informative mutations in this respect are the M64T/R76P CaM-NLS and R133W β-NLS (see [ 10]) mutations, none of which markedly affects DNA binding and bending, all only specifically impairing the nuclear import pathways mediated by the NLS in which they are mutated.

While the wild type Roc1a transgene was able to rescue the lethality of the Roc1aG1 mutation, none of 5 different ANBR transgenic insertions were able to do so (Fig. 4A).

So far, only two members of the family consented for predictive testing for the MSH6 mutation, none of which carried the mutation.

Looking more specifically at the mutation type, there is much variability in the effect of adjuvant chemotherapy among the patients harbouring a codon 12 mutation, none of them being significant due to the size of the samples.

Of the 1549 MTCs in the COSMIC dataset, 625 (40.3%) exhibited a RET mutation, none of which were Y791F, indicating that there is not a frequent association between this variant and MTC tumourigenesis (Supplementary Table 4, see section on supplementary data given at the end of this article).

Among the reports of 16 kindreds with 12 different amelogenesis imperfecta (AI) causing ENAM mutations, none revealed a history of systemic problems associated with the genetic condition.