Sentence examples for mutations needed to from inspiring English sources

In a purely mutational phylogeny, imperfection corresponds to the number of recurrent mutations needed to explain the data set.

The H5 virus has been present in the human population since the late 1950's, said Dr. Offit of Children's Hospital, but has never acquired the full set of mutations needed to set off a pandemic.

By withholding key details of the mutations needed to make an airborne strain of H5N1, this would give time for governments to prepare for and prevent a possible pandemic, he added.

Once his team achieved transmission in the summer of 2011, the researchers began additional experiments to identify the minimum set of mutations needed to make the virus airborne.

The number of mutations needed to confer high-level resistance to PIs is lower in HIV-2 [ 9].

Normal mutation rates are thus quite sufficient to explain the crucial mutations needed to drive tumorigenesis, but how many mutations exist within a typical cancer?

The resulting distribution will strongly depend on the number of mutational steps analysed, so n different mutations need to be analysed for one measurement of epistasis in order to understand n-step epistasis.

Depending on their efficacy, safety profile and approval by regulators, oligonucleotides targeting additional exons to address other mutations need to follow, through more tailor-made, shorter, development programs.

In addition, intra-tumor heterogeneity with the presence of clones of tumor cells lacking BRAF mutations needs to be considered, since wildtype BRAF can be activated by inhibitors designed to target mutated BRAF.

One blow to Fisher's theoretical solution came when Crow and Kimura (1970) noticed that mutations need to have a certain minimal effect on fitness to become selected, establishing a limit to evolution by very small steps.

The key obstacle to developing functional genotyping assays is that such mutations need to be genotyped regardless of their location in genomic regions.