Sentence examples for mutations modifying the from inspiring English sources

Mutations modifying the DNA methylation machinery in A. thaliana lead to mobilization of TEs [ 79].

The duplication of pre-existing genes had profound evolutionary implications for the developmental complexity in vertebrates, since mutations modifying the function of a duplicated protein can lead to novel functions, improving the evolutionary success.

Effects at the molecular level are unknown, but it appears that mutations modifying the active site are rare, given that only one mutation was found in proximity to the catalytic site.

Thus, even though selection should favor point mutations modifying the repeat sequence purity, which would decrease the propensity toward further disease-causing repeat accumulation, repeat sequence in disease-associated coding regions is more highly conserved than in nearby non-coding regions.

Recently, various genes have been identified whose mutations modify the life span of certain animals.

Genetic mutation is the ultimate source of novelty in biological evolution but again, the vast majority of mutations modify the nature of preexisting structures rather than produce utterly new features.

Several epigenetic diseases are already known that may be inherited through the somatic and the germinal line: fragile X syndrome, in which ATRX gene mutations modify the methylation pattern of ribosomial RNA and, by methylation of CGG expansions in the FMR1 gene, silence the gene; the Angelman and Prader-Willi, and Rett syndromes; also, many colonic cancers and leukemias.

While the donor side mutations changed systematically the number of H-bonds to P, the acceptor side mutations modified the energetics of QA by altering the van-der-Waals and electronic interactions (M265IT) and H-bond network to the acidic cluster around QB (M234EH, M234EL, M234EA and M234ER).

For instance, during evolution, mutations modify the architecture of brains and external appearances, novel behaviors appear and reciprocal lethal/sterile genetic systems emerge to block gene flow.

We examined whether the HFE mutations modify the impact of lead on PP in community-dwelling older men.

Ben Lehner (European Molecular Biology Laboratory - Centre de Regulació Genòmica, Spain) presented exciting results from Caenorhabditis elegans experiments showing how some gene mutations modify the effect of mutations of other genes.