Sentence examples for mutations modifications in from inspiring English sources

Various mechanisms affect gene expression in tumoral cells, including copy number alterations, mutations, modifications in the regulation network between the genes.

Mutations or modifications in disease-specific proteins can cause misfolding and consequently formation of aggregates.

Inherited stable changes in cell functioning that cannot be explained as the result of mutations or modifications in the DNA sequence are considered as epigenetic (Bird, 2007).

These mutations introduce modifications in both tunnel topologies and affect the incoming ligand capacity to displace retained water molecules at the active site.

Abstract: line 12 The sentence "mutations introduce modifications in both tunnel topologies" is quite cryptic and it is not clear what the author mean with "tunnel topologies".

We rephrase the sentence "These mutations introduce modifications in both tunnel topologies and affect the incoming ligand capacity to displace retained water molecules at the active site".

Corrected, thanks  Abstract: line 12 The sentence "mutations introduce modifications in both tunnel topologies" is quite cryptic and it is not clear what the author mean with "tunnel topologies".

We have discussed genomic mutations and epigenetic modifications in pediatric asthma and ASD.

In this context, Wang proposed that in order to enhance the detection rate of somatic mutations or epigenetic modifications in circulating blood DNA, a method selectively extracting small DNA fragments should be used.

It is thus important to identify potential environmental factors that contribute to the increased rate of de novo mutations and/or epigenetic modifications in the parents (Kinney et al., 2010).

TSGs are frequently dysregulated by mutations or epigenetic modifications in both hereditary cancer syndromes and/or somatically non-hereditary cancers and are also responsible for the initiation and progression of all types of cancers, thereby composing an essential class of signalling molecules within the cell.