Sentence examples for mutations may therefore from inspiring English sources

Such mutations may therefore affect heterodimer formation.

These mutations may therefore contribute more to cancer formation and development than other mutations.

Inactivation of PRDM5 through gene deletions, epigenetic silencing or point mutations may therefore represent a novel mechanism of constitutive activation of wnt signaling in human tumors.

By altering interactions between peptide/MHC class I complexes and immunomodulatory MHC class I receptors on myelomonocytic cells, CTL escape mutations may therefore have important, previously unrecognized regulatory effects on the functional profile of dendritic cells and monocytes.

The mutations may therefore result in a loss of function by preventing DNA binding or nuclear import.

Since most genetic variants identified by genome-wide association studies (GWAS) are located outside coding genes, many of these mutations may therefore affect lncRNAs.

The Ftind51 mutation may therefore also be linked to virulence in the strain FSC043.

Given the increase in MDR1 expression, we hypothesized that Apc mutation may therefore confer chemotherapeutic resistance.

Interestingly, Arg105 is a key residue in collagen recognition (Fig. 2C) and its mutation may, therefore, inactivate the receptor.

The observed lack of decrotonylation activity upon mutation may therefore be a consequence of disrupted NAD binding rather than demonstrating substrate selectivity.

The 'Neu' mutation may therefore not activate by enhancing dimerization but by increasing the probability at which transiently stable complexes, resulting from random collisions, switch stochastically into an active state.