Sentence examples for mutations may shift from inspiring English sources
So, although elevating the mutation rate may reduce fitness through the influx of deleterious mutations, as fitness declines the ratio of beneficial to deleterious mutations may shift to a point at which a significant proportion of new mutations are beneficial, or compensatory, and their collective effects begin to elevate fitness.
Taken together, these results support LRRK2 as a positive regulator of inflammation in microglia, and disease-related LRRK2 mutations may shift the microenvironment of the brain to favor neuroinflammation.
Loss of RASSF1A expression by methylation may shift the balance towards a growth-promoting effect without the necessity of activating K-ras mutations.
Loss of RASSF1A expression may shift the balance towards a growth-promoting effect without the necessity of activating K-ras mutations.
However, mutations that alter the strengths of either these decoys or the natural splice site of the same polarity may shift the balance of isoforms towards non-constitutive splice isoforms that predominate over or eliminate normal mRNAs.
The battle may shift back to Washington.
This may shift with the next generation.
The posterior portion may shift laterally.
This study suggested that certain ER mutations may facilitate shift of helix 12 of ESR1 into a conformation that mimics the ligand-bound active state of the receptor [ 33].
