Sentence examples for mutations may decrease from inspiring English sources
The number of expected mutations may decrease as new genomes are sequenced; however, such a high number of errors turns variant discovery into a 'needle in a haystack' problem.
Some mutations in Cx26 and Cx32 have been recently mapped to areas of the transmembrane helices of these connexins, suggesting that certain disease-causing mutations may decrease the stability of the connexons [ 211].
Finally, NOD2 mutations may decrease the expression of the regulatory cytokine IL-10 in dendritic cells at least, which may implicate NOD2 in disordered regulation of inflammatory cytokines, such as TNF, IL-12 and suppressor T cells, and allow for an aberrant inflammatory response [ 136].
Therefore, the Nrg1p P46Q mutation may decrease repression of Nrg1p-controlled genes.
The sport may decrease symptoms of PTSD.
Using e-prescription software embedded within the EHR system, his health care provider prescribes an NNRTI and is concurrently prompted to order a genotype resistance test to identify mutations that may decrease the NNRTI's effectiveness; the order is added with a single click from the alert screen.
Using combined wild genotype CC/GG/TT as control, combined mutation genotype CT/GG/CT may decrease the risk in developing ESCC (OR: 0.46, 95% CI: 0.22 0.96, P = 0.04).
In one simple case, if selection is intermittent, a haplotype that is driven to fixation during one episode of strong selection may experience subsequent changes during a period of relaxed selection (these mutations may increase, decrease, or not affect resistance), in which case the eventual path taken may include non-favored and/or double mutations.
We previously demonstrated that the sodium channel mutations may significantly decrease channel sensitivity to mexiletine, while effects of flecainide are preserved, thereby opening the way toward a pharmacogenetics strategy (Desaphy et al., 2001, 2004, 2013a).
Mutations within this region may decrease translation efficiency [ 5].
His health care provider prescribes a non-nucleoside reverse transcriptase inhibitor (NNRTI) and concurrently orders a genotype resistance test to identify HIV-reverse-transcriptase-based mutations, as certain variants may decrease the effectiveness of the prescribed inhibitor.
