Sentence examples for mutations make up from inspiring English sources

These mutations make up an allelic series with differing strengths of transformation (lowering the Ubx expression in PS6).

DNA replication errors that persist as mismatch mutations make up the molecular fingerprint of mismatch repair (MMR -deficient tuMMR -deficienty tumorsith resistande to standard therapy.

For example, in patients of African ancestry, 3 mutations make up 60.5% of all the LRs detected, with BRCA1 duplication exons 18-19 alone constituting 33%.

Mutations in other genes are rare; APOB mutations make up 2%5%% of cases, and mutations in PCSK9 and LDLRAP1 each make up <1% of all FH cases.

In patients of Latin American/Caribbean ancestry 5 mutations make up 81.5% of all the LRs detected, with a single LR, BRCA1 deletion exons 9-12, comprising 37%.

Considering an estimate for the rate of all mutations (i.e., including neutral and deleterious mutations) of order 10−3 (Drake et al. 1998) means that beneficial mutations make up ∼1% of the total number of mutations.

For several genes, a limited number of recurrent mutations made up the majority of mutated alleles.

Deleterious mutations made up the majority of the dataset and also contained the greatest number of keywords: decrease, inhibit, reduc, loss, lower, abolish, abrogate, inactive, diminish, disrupt, impair, eliminate, no activity, prevent, suppress, increases km, increases the km.

Sequencing of 2 P. falciparum multidrug resistance 1 (pfragmentsasments as described (5 ) detected only the N86Y, Y184F, and N1042D mutations making up 5 haplotypes.

The families studied here, who carry the ALK mutation, make up a tiny minority of those affected by neuroblastoma, however.

Humans harboring a germ-line inactivating p53 mutation make up 50% of the members of the Li-Fraumeni cancer predisposition syndrome.