Sentence examples for mutations it will from inspiring English sources

In parallel with developing model systems for these mutations, it will be necessary to assess their penetrance and to establish whether more subtle phenotypes (for example, dyslexia or anxiety disorders) occur in seemingly unaffected individuals.

Therefore, in patients with THRA mutations, it will be important to characterize the functional properties of their mutant TRα1 because this may predict their response to T4 treatment and the optimal systemic T4 concentration required.

Ultimately, to confirm the identification of each suppressor locus and to exclude possible contributions from closely linked mutations, it will be necessary to reintroduce each suppressor mutation in a clean unmutagenized background.

In taxa where there is an appreciable number of beneficial mutations, it will be interesting to see whether amino acid identity is also correlated with the rate of change.

The longer a variety evolves, the more mutations it will accumulate and the more homoplasy will be able to occur and consequently to scramble the evolutionary signal, leading to higher variance.

As we discover the distinct biochemical and cellular phenotypes associated with Parkin mutations, it will be interesting to determine whether these correspond to differences in clinical presentation and/or disease progression.

They now plan to try growing ovary stem cells from common frogs and, when they find a technique that works, remove some of the yellow-legged frog cells from the cryogenic chamber and test it on them.Although this particular batch of cells is unlikely to be used for assisted reproduction because of the donor's heritable mutation, it will help scientists work the process out.

From now on, the appearance of new and different life forms will not be merely the result of random mutation; it will be deliberately planned and chosen by us.

Conversely, if it does inherit the GCK mutation, it will produce normal amounts of insulin, despite the higher level of glycemia, and thus growth will be normal.

If the mutation is a germline mutation it will be picked up on dHPLC screening of germline DNA, however, a somatic mutation would be missed in both tumor and germline DNA without DNA mixing.

As the possibility exists that the 5'-UTR polymorphim may be in linkage disequilibrium with the G79C mutation, it will be interesting to investigate both polymorphisms in samples from healthy and diseased donors.