Sentence examples for mutations it becomes from inspiring English sources

In order to study the structural importance of cTF and the effect of associated disease mutations, it becomes essential to construct a three-dimensional model of cTF.

Once a cell has accumulated all the necessary mutations, it becomes fully malignant and can subsequently (after some lag period) develop into a clinical cancer.

When any cell within the clone acquires a second oncogenic mutation, it becomes a fully malignant cell, which can grow into a clinical cancer.

But, when the tumor cells contain the BRAFV600E mutation, it becomes clear that this subset of tumors behaves very differently than wild-type (WT) cells in regard to their propensity to activate autophagy and the importance of autophagy for cell survival.

It seemed that natural selection has weeded out any disease-causing mutation before it becomes common.

Using a spectrum of recent measurements of microbial background mutation rates, it becomes possible to at least loosely estimate the average elapsed time since isolation between YNP chemotrophic communities (discussed below) as a way to speculate on plausible bottleneck events.

As shown in table 3 both under low and high mutation rates it becomes increasingly difficult to find individual based solutions.

That is, under lower mutation rates an individual based solution is evolved in almost all cases (blue and green) and under increased mutation rates it becomes increasingly difficult to reach an individual based solution.

Delbrück soon began to collaborate with Luria, and in 1943 they announced their discovery that a bacterium that has been infected by a bacteriophage can undergo spontaneous mutations so that it becomes immune to the phage.

However, the introduction of genomic approaches makes it easier to detect mutations and consequently it becomes more difficult to decide on the definitions of hiPSC quality.

Although we were interested in determining as many mutations as feasible, it becomes too laborious when the number of lines to be crossed is large.