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However, a multiethnic study on BC Malaysian demonstrated that the frequency of TP53 mutations is superior to BRCA1/2 genes alterations especially in patients with positive family history which could make BRCA1/2 mutation screening debatable [ 109].
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The determination of temperatures of half-maximal irreversible denaturation revealed that a combination of the two mutations was superior to the single mutations and the insertion of additional residues was considerably better tolerated in the stabilized libraries.
In mutIV-mix-2 however only the second mutation which lies within the RNAse domain was found, indicating that this mutation is superior to the other and thus propagated across all strains during the prolonged cultivation.
Genotypes with this mutation are superior competitors on acetate, but are inferior to derived glucose specialists when only glucose is available.
The Pyrosequencing technology [ 21] has an analytical sensitivity for detection of mutations that is superior to that of Sanger (dideoxy) sequencing.
Therefore, our limited experience indicates that EGFR mutations may be superior to smoking history in the selection of patients who would benefit from TKI treatment and that smoking history is only a surrogate marker of EGFR mutation.
Therefore, we conclude that the RAS pathway signature is a transcriptional readout of RAS dependence that has utility for drug response prediction that is superior to KRAS mutation status.
21 22 It has recently been demonstrated that an RAS pathway signature is superior to KRAS mutation status for the prediction of dependence on RAS signaling, and can predict response to PI3KCA and RAS pathway inhibitors.
These data demonstrate that the RAS pathway signature is superior to KRAS mutation status for the prediction of dependence on RAS signaling, can predict response to PI3K and RAS pathway inhibitors, and is likely to have the most clinical utility in lung and breast tumors.
These results suggest that T7 endonuclease I is superior to Surveyor nuclease for detecting indel mutations in target DNA.
Large Γ is superior at small pairwise distances, which corresponds to a regime of few large effect mutations.
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