Sentence examples for mutations is substantial from inspiring English sources

All these experiments demonstrate that the input of new variation through de novo mutations is substantial and may explain part of the response to selection during the course of adaptation in natural populations.

Now, notice that there is substantial mutation and recombination hotspot activity in the α- and β-globin gene clusters [ 234, 236].

If the chance of multiple mutations in a single lineage is substantial [e.g., if (μ Tor) > 0.01], then equation (4) will be an overestimate.

The additional risk of thrombosis during pregnancy associated with such genetic mutations can be substantial.

"An anorak is substantial.

Yet the gain is substantial.

But the number is substantial.

"That is substantial funding".

The height effect is substantial.

The taste effect is substantial.

And the difference is substantial.