Sentence examples for mutations is problematic from inspiring English sources

Identification of the molecular basis of lethal mutations is problematic for WGS because the animals cannot be grown as homozygotes in large amounts for DNA production.

As I alluded to in previous comments, mutation of this aspartate is problematic, since it has a negative effect on nucleotide binding, making the interpretation of the results difficult.

In general, longer reads are desirable, especially where mapping the location of a sequence is problematic and mutations other than base substitutions are expected, but there appears to be a trade-off between read length and factors such as cost and, arguably, accuracy.

Our inclusion of transposition as a possible mechanism for gene order mutation in the Campanulaceae chloroplast genomes is problematic.

We find that identification of mutations other than substitutions, e.g. deletions, is problematic.

In patients with KRAS mutations, the choice of the most appropriate treatment is problematic.

The high EC50 value is problematic for measuring loss-of-function mutations for many reasons.

8) The terminology used to describe mutations in the discussion of Figures 5 and 6 is problematic.

Such a comparison is difficult because estimating the "mutation rate" in the spatially structured bacterial cells of biofilms is problematic.

The omission is problematic.

Its availability is problematic.