Sentence examples for mutations is lethal from inspiring English sources

Similarly, an unknown fraction of mutations is lethal and not ascertained as pathogenic.

The screen took advantage of the fact that a combination of sepF and ftsA null mutations is lethal (Ishikawa et al, 2006).

Furthermore, no plasmid-less colony could be obtained from Inv dinG rep recA; [pAM-rep] cells even on MM, indicating that in both Inv backgrounds the dinG rep recA combination of mutations is lethal (Supplementary Table S3; uvrD recA colonies were slow growing on LB and were not affected by inversion, Supplementary Table S3).

We could not determine the Bah phenotype of daf-2 null mutations, because such mutations are lethal [44].

Several SCF knockout animals have been described whereby most homozygote SCF mutations are lethal due to severe anemia [40].

In our studies, we found that E74BG01805 homozygotes survive to adulthood, presumably because the mutant retains residual E74 function (null E74 mutations are lethal).

Four of the alanine mutations were lethal: E89A, E124A, R135A, and R136A.

Consider the extreme case that all mutations are lethal and furthermore that they are lethal regardless of strand.

First living systems had much simpler interpretation machinery, than contemporary cells; thus, most of their mutations were lethal.

While dumpy null mutations are lethal, some hypomorphs produce wings that are short and misshapen a defect that arises during pupal development (Waddington, 1939, 1940).

One possibility is that these mutations are lethal at an early embryonic stage; a second possibility is that investigators have not looked in the right phenotypic group.