Sentence examples for mutations is indeed from inspiring English sources

In view of these results, we would conclude that the 9q31 locus that appears associated with HSCR in families bearing no RET CDS mutations is indeed population specific, as the findings in Chinese point to a different locus with a completely different genetic behaviour than that identified in the Dutch.

Further investigation of the fitness effects associated with synonymous mutations from these experiments typically reveals that these mutations are indeed neutral18,19.

Whether these mutations are indeed causative and what types of digenic variations may be responsible for LCA needs additional study.

Acquired drug-resistance mutations were indeed observed in all plasma samples sequenced after failure (data not shown).

Defenses against unpredictable threats (parasites, fluctuating environment and deleterious mutations) are indeed significantly improved by wider genetic variability and by positive epistasis gained by sexual reproduction.

A number of resistance mutations are indeed termed compensatory or secondary drug resistance mutations since they restore at least partially the enzyme function possibly compromised by the true resistance mutation(s).

To demonstrate that tubulin mutations were indeed responsible for causing the BPR0L075-resistant phenotype, gene transfection and over-expression of the βI-tubulin mutant that contains the above mutations was performed in KB cells.

To confirm that these mutations are indeed responsible for the synthetic lethality with rps15-1, we crossed the Ins9 and Ins15 strains to either the Δnhp2::kanMX4, rps15-1 or Δutp15::kanMX4, rps15-1 null mutants respectively.

A significantly higher number of G mutations was indeed observed in the WRC or GYW motifs in NBS patients (Fig. 2 and Table 2), whereas G residues outside these motifs were targeted equally (11.3% vs. 11.1% of total mutations in controls).

Such mutations are indeed observed in several types of human cancer including melanoma.

The results of the present study support earlier findings that such mutations are indeed infrequent in this type of tumour.