Sentence examples for mutations is generally from inspiring English sources

Also, it has to be emphasized that current large screening initiatives based on primary airway cells are not able to target rare CF mutations, since explanted lung tissue homozygous for rare mutations is generally not available.

The frequency of codon 61 mutations is generally believed to be low.

Although information on germline polymorphisms in microRNAs is growing, the occurrence of somatic mutations is generally much less well understood and less commonly identified.

The phenotypic outcome of Apert syndrome mutations is generally similar, such that genetic testing is required to identify the causative mutation.

As resistance to nalidixic acid due to first-step resistance mutations is generally thought to precede resistance to fluoroquinolones (19), close continued monitoring of resistance rates to both these drugs among nontyphoidal salmonella is warranted.

In contrast to KIT mutations, the frequency of BRAF mutations is generally low in mucosal melanomas and does not seem to vary significantly between different sites (Omholt et al, 2011).

These mutations were generally found to be IS 6110 strain lineage-specific, although examples of additional within-lineage and even within-cluster mutations were observed.

One of these approaches is based on pathogenic mtDNA mutations being generally heteroplasmic, with observable pathology only present when the ratio of mutated mtDNA exceeds a certain threshold.

The many available crystal structures of RT reveal that, generally, in relation to their binding sites NRTI resistance mutations are generally more distally positioned, whilst for NNRTIs mutations are clustered.

ATR-X patient mutations are generally hypomorphic and do not cause chromosomal instability[4].

However, microdissection and sequencing of breast cancer samples suggest that p53 mutations are generally, if not virtually always, clonal within breast cancer [30], [31].