Sentence examples for mutations is complex from inspiring English sources

The pattern of epistatic interactions between the specific mutations is complex and dependent on environmental factors such as the presence and absence of drugs and the host cells used.

The management of women with BRCA mutations is complex, requires a multi-disciplinary team approach and includes counselling about cancer risk, surveillance options and discussion of risk-reducing surgery including prophylactic mastectomy and/or oophorectomy.

However, a reliable method to quantify either mutant is not available, partly because the viral genome has polymorphisms in general and the precore mutations are complex.

The mechanisms proposed for the pathogenesis of these mutations are complex and likely to be multifactorial.

The relationship between high EGFR copy number and EGFR mutation is complex.

Since the theory proposed here holds that mutation is nonrandom and combines information from multiple loci, it predicts that the determination of mutation is complex.

As a result, we suggest that cryptic variation in the mutation rate is complex, in the sense that the mutation rate does not appear to depend on any specific context.

Mutation detection is complex, due to the large gene size, the large variety of mutations and the presence of pseudogenes.

A factor that may be considered in a combined battery is cognitive scores, although the relationship between cognition, LRRK2 mutations, and olfaction is complex.

The interpretation of a mutation as pathogenic is complex and not always possible, although a significant recent advance has been made with a standardised classification scheme [ 2].

It is apparent from our B-SIFT analysis that the systematic prediction of activating mutations is more complex than the analogous prediction of deleterious mutations.