Sentence examples for mutations is able from inspiring English sources

Taken together, our experimental data indicate that expression of both the p.Ser59Leu and p.Pro34Ser CHCHD10 mutations is able to decrease the sensitivity of the cells toward apoptotic stimuli.

To explore the extent to which the idealized SBD model assuming infinitesimal mutations is able to infer fitness when evolution happens via discrete mutations, we simulated a simple model of evolution with fixed fitness variance (σ = 0.03 ) (Zanini and Neher, 2012).

Although the presence of the A2143G mutation was rare in the present study and the A2142G mutation demonstrated the highest frequency observed, the clinical relevance of this distinction has a limited value, since the presence of either of these mutations is able to confer clarithromycin resistance [ 22].

Our work demonstrated for the first time that both SOD1 +/and2C and FUS +/G1566A mutations are able to be corrected by CRISPR/Cas9-mediated gene editing technique in ALS patient specific iPSCs.

However, it is uncertain whether Salmonella PhoPc and its derived mutations are able to colonize the intestine in vivo.

However, the exact mechanism by which NOD2 mutations are able to induce CD lesions is still subject to debate [7] [10].

None of the single mutations was able to abolish Nrf2 phosphorylation as well as the combined 5A mutation, suggesting a redundancy in phosphorylation sites (Figure S1).

Exon 9 and exon 20 PIK3CA mutations were able to be analyzed separately and, indeed, only exon 20 mutations were found to be associated with a worse outcome after cetuximab administration.

When tested in a second maternal enhancer screen, only a few these mutations were able to reduce signaling of the ligand Decapentaplegic (DPP) and cause embryonic lethality in combination with the allele dpphr4 [10].

Based on my previous results of 3.5 point mutations/[Kb] in vertebrate genomes [6] and the fact that only 4 out of 6 point mutations are able to interrupt pure GA-sequences, one would expect a total of 4213 point mutations, or more than 160 times as many as were actually found.

Animals homozygous for ico null mutations are able to survive on maternal contribution to the larval stages but fail to initiate the rapid growth phase during the third larval stage, which is not surprising given the role of EF-G1 in mitochondrial biosynthesis and the high energy demands during that phase.