Sentence examples for mutations involving a from inspiring English sources

If the dynamics of return to equilibrium are driven by local mutations involving a stepwise mutation model, then V returns to equilibrium much more slowly than HE.

We identified 4 novel ETNK1 mutations involving a total 10 patients (N244S=6, N244T=1, N244K=1 and G245A=2; Figure 1).

Most BRCA1 or BRCA2 gene aberrations are small mutations involving a single or multiple changes in nucleotide sequence, but large genomic rearrangements (LGRs) have also been reported in patients who are negative for BRCA1 or BRCA2 sequence variations.

The stand-out result is the predominance of missense/non-sense mutations (i.e. mutations involving a single base substitution): around half of published mutations in humans and in non-laboratory animals are missense/non-sense.

Missense mutations involving a cysteine residue (either gain or loss) in the EGF repeats is a hallmark for CADASIL mutations in NOTCH3 [ 33], but we did not find any missense mutations affecting cysteine residues in the CCLE data set.

The two phase model of DiRienzo et al. (1994) is a modification of the SMM with most mutations involving a gain or loss of a single repeat and the remainder of the mutations being multi-step mutations following a geometric distribution.

The most appealing initial target has been BRAF itself, as most mutations involve a single residue in the kinase domain of the protein.

Compensatory mutations involve changing both members of a base pair (i.e. GC→AT) to preserve the secondary structure, whereas consistent mutations involve a change to only one member of the pair while preserving secondary structure (i.e. GC→GU).

All new mutations involved a single nucleotide.

These so-called 'nonsense' mutations involve a PTC.

(B ) The codon mutations involve a mix of one-, two-, and three-nucleotide mutations.