Sentence examples for mutations involve a from inspiring English sources

The most appealing initial target has been BRAF itself, as most mutations involve a single residue in the kinase domain of the protein.

Compensatory mutations involve changing both members of a base pair (i.e. GC→AT) to preserve the secondary structure, whereas consistent mutations involve a change to only one member of the pair while preserving secondary structure (i.e. GC→GU).

These so-called 'nonsense' mutations involve a PTC.

(B ) The codon mutations involve a mix of one-, two-, and three-nucleotide mutations.

Over 80% of the BRAF mutations involve a missense mutation that results in the substitution of glutamic acid for valine at amino acid 600 (V600E).

More than 90% of BRAF mutations involve a single point mutation, T1799A, in codon 600 of exon 15, leading to a V600E amino acid substitution [ 9, 10].

Less frequent mutations involve an evolutionarily conserved 15 20 residue segment of the TRD known as Myc Box II (MBII) [6], [7], [8], [9], which contributes importantly to the transforming function of Myc and is a site of several significant protein-protein interactions that influence transformation [10], [11], [12], [13].

Only one of the mutations involves a contact residue, whereas the other two have indirect effects on the shape of the combining site.

If the dynamics of return to equilibrium are driven by local mutations involving a stepwise mutation model, then V returns to equilibrium much more slowly than HE.

All new mutations involved a single nucleotide.

In particular, most of these mutations involved a cytosine base that was preceded by a thymine base.