Sentence examples for mutations introducing the from inspiring English sources

For the efficient generation of saturation and positional scanning mutagenesis variants, mutations introducing the unique restriction sites AgeI and Eagl were engineered at nucleotide positions 255 and 282, respectively, in the lexA coding sequence using QuikChange site-directed mutagenesis.

Importantly, this mutation introduces the only Cys in the entire recombinant H4 sequence.

Additionally, these findings indicated that the mutations introduced in the C-ter domain did not affect the overall structure of the chemokine.

ENU mutations occur systemically, however, only the mutations introduced in the germline are passed on to the next generation.

Hence, the mutations introduced into the HA sequence totally abrogated furin-mediated proteolytic activation.

Mutations introduced in the NLS of the EGFR-ligand SwGF result in the loss of its mitogenic activities.

The new assay permits the analysis of the effects of specific mutations introduced into the cloned element.

The other mutations introduced in the active site (Lys96Gln, Ala134Val, Cys138Ala, Asp49Gly, His51Ala, His57Asp, Trp68Leu, and Phe13Leu) had very similar effects.

Episomal gene repair assays were performed with ssODNs designed to target the point mutations introduced into the two reporter genes.

Simulation ended when the number of mutations introduced equals the preset number (dl/ a).

(A) Point mutations introduced to the Zn2+-coordinating residues render the METTL3-METTL14 methyltransferase inactive.