Sentence examples for mutations introduced to from inspiring English sources

Mutations introduced to wild-type proteins naturally, or intentionally via protein engineering, often lead to protein aggregation.

We measured the effects of various mutations introduced to the L2 loop's region (residues 228 238) on the stability of HtrA molecule and its proteolytic activity.

(A) Point mutations introduced to the Zn2+-coordinating residues render the METTL3-METTL14 methyltransferase inactive.

However, there were a number of other "off-target" mutations introduced to the genetic code.

Although spatially the mutations introduced to disassociate CH3 dimerization are distant from the FcRn binding region in CH2-CH3, Half DVD-Ig molecules that have the F405R or other CH3-mutations exhibited significantly reduced serum half-life.

Mutations introduced to the M150B genome were identified by sequence comparison to the wild-type and published closed sequences.

As MKK4 and MKK7 were previously reported to harbor two LF cleavage sites [27], two cleavage-resistant mutants with the aliphatic-to-aspartic mutation introduced to one of the cleavage sites were generated for each of MKK4 and MKK7: V5-MKK4cr_46 and V5-MKK4cr_59 for MKK4, and V5-MKK7cr_45 V5-MKK7cr_77r_77 for MKK7 (Figure 2E and F).

Mutations were introduced to alter all AAG/AGA/GAA trimers in exon 9 by mutating the Gs to Cs.

Mutations were introduced to the domain-swapped homodimer of the antiviral lectin griffithsin (GRFT).

Mutations were introduced to the bacterial SPL from Symbiobacterium thermophilum which mimic the human enzyme.

Null mutations were introduced to bring down these ΔG levels below −5.0kcal/moll.