Sentence examples for mutations into an from inspiring English sources

Dr Fouchier and his colleagues introduced the three mutations into an Indonesian strain of H5N1, then tested the virus in ferrets.On its own, the mutated virus did little.

Modeling human disease has further become possible with advances in genetic modification in hESCs either through homologous recombination (Song et al., 2010; Hockemeyer et al., 2011) or gene knockdown (Ordonez et al., 2012), as well as reprogramming of cells having disease-causing mutations into an ESC-like state (human induced pluripotent stem cells or hiPSCs) (Unternaehrer and Daley, 2011).

Therefore, we hypothesized that introducing these two mutations into an MPER-based HIV-1 vaccine candidate might increase its immunogenicity to elicit stronger MPER-specific antibodies with broad neutralizing activity.

As a test for specificity, we introduced the same set of rpn1 mutations into an rpn4Δ background.

This strain was selected to avoid potential biological safety issues of introducing known antimicrobial resistance mutations into an invasive human pathogen.

Typhi BRD948) is a well-studied non-invasive laboratory strain and was selected to avoid potential biological safety issues attributed to introducing known antimicrobial resistance mutations into an invasive human pathogen.

Different in vitro chemical mutagenesis methods have also been used to introduce random mutations into a gene of interest.

They are commonly used method to give the irregular variations of mutations into a defined segment and specific of the DNA (Hou et al. 2015).

Additionally, engineering the TS1 or TS2 mutations into a distantly related human seasonal H1N1 influenza A virus also resulted pronounced restriction of replication in vitro.

In the current study, the impact of well considered point mutations into a bioactive peptide that was found to be a very potent and selective inhibitor of NaVs (i.e. Midi R2) was examined.

However, reintroduction of single as well as combinations of mutations into a WT background identified D320E as the single mutation conferring part of the observed genome-associated resistance.