Sentence examples for mutations indicates that from inspiring English sources

Simulating the mutational catalogs of 50 cancer genomes with different average numbers of mutations indicates that two or three signatures can be effectively extracted from catalogs with very few mutations, whereas extracting seven or more signatures requires an average of at least 1,000 mutations per catalog.

A detailed analysis of these mutations indicates that most of them are artifacts of the segmentation procedure, which creates very small segments in the normal samples that are not present in the tumor samples.

The presence of sequence variations and polymorphisms in CpG islands of L1 promoters that arise from transition mutations indicates that CpG methylation could play a significant role in determining the activity of L1 elements in the mouse genome.

Although circular viral DNA is a dead end product that is not on the integration pathway, the effect of these mutations indicates that MA is functionally associated with the PIC and can influence the viral replication pathway after reverse transcription.

Eight of these mutations were reported as novel, a finding that was interpreted by the authors as follows: "the identification of these mutations indicates that mutations in mtDNA may account for a significant portion of genetic etiology in Noonan syndrome" (p. 287) [18].

In addition, analysis of TTN mutations indicates that these are likely to be artifacts [ 41].

For most parameter values in case 1, α50% remains within the range of α for commonly observed mutator mutations, indicating that mutator pathways will have a significant role in tumorigenesis.

Distinct gene mutations indicated that lizards from southern and southeastern Florida largely hailed from western Cuba.

In addition, almost 80%% of highly expressed non-TE genes have insertion mutations, indicating that highly expressed genes in rice chromosomes are more likely to have mutations by mutagens such as T-DNA, Ds, dSpm and Tos17.

Although linear regression modeling is a statistical data-driven technique focused on obtaining the best possible prediction, many of these mutations are also known resistance-associated mutations, indicating that the statistical models largely reflect well characterized biological phenomena.

At three locations where the chimp and human genomes were almost identical, telltale mutations indicated that it was impossible to get a viable protein from the chimp DNA sequence.