Sentence examples for mutations increased with from inspiring English sources

Consistently, the mutational load, which incorporates both the number and clonality of mutations, increased with increasingly severe histological class of BE, suggesting that mutational load is a relevant measure of genetic damage that can provide additional, objective information to the existing histological classification.

In neurons from the neurologically normal people, the number of genetic mutations increased with age in both brain areas.

The prevalence of the HBc141 149 mutations increased with the disease progression in HBV-infected patients (Fig. 5D).

The percentage of patients with p16 mutations increased with increasing histologic grade.

It is noteworthy that the fraction of beneficial mutations increased with robustness, at least in the simple environment, whereas the magnitude of beneficial mutations did not significantly change.

We confirmed that the number of mutations increased with repeat length at a much higher frequency than was expected from the occurrence of such repeats in the genome.

On the other, if germ-line mutations increase with age, older males could produce relatively unfit offspring.

Mutational load was positively correlated to histological classification, with the number and clonality of mutations increasing with increasingly severe histological classification.

Our study confirms an earlier report that microsatellite mutations increase with age and is the first to provide evidence that these mutations may be associated with cancer status in individual subjects.

Indeed, it is well known that mtDNA mutations increase with age, and recent findings show that this increment is likely due to errors in replication machinery or to unrepaired damage, placing ROS mutagenic effect in the background.

The observation that frequency of mutation increased with histologic grade suggests these patients may have experienced a longer or more intense exposure to oxidative damage induced by reflux.