Sentence examples for mutations including nucleotide from inspiring English sources

15 mutations, including nucleotide deletions and substitutions, were identified in 14 lines from 90 independent transgenic plants (Figure 1b), indicating sgRNA Cas9-induced gene targeting in rice.

For this type, the differentiation between R and S alleles is primarily caused by localized mutations, including nucleotide substitutions, small insertions/deletions (InDels), and insertion of transposable elements.

The first type is small-scale point mutations, including nucleotide substitutions and short insertions or deletions.

Since humans and chimpanzees diverged 5 7 million years ago [ 1, 2] their genomes have acquired a multitude of lineage specific mutations, including nucleotide substitutions, insertions and deletions (indels), duplications and inversions.

After mtDNA inserts into a chromosome, the resulting NUMT gradually accumulates mutations, including nucleotide substitutions and the insertion of other sequences, such as transposable elements, all of which contribute to the degradation of the NUMT over time (Ueda et al. 2005; Kleine et al. 2009; Michalovova et al. 2013).

Information collected included the year of birth; mutation description, including nucleotide position and base change; age at last follow-up; ages at breast and ovarian cancer diagnoses; and age or date at bilateral prophylactic mastectomy.

Information collected included the year of birth; mutation description, including nucleotide position and base change; self reported ethnic ancestry, age at last follow-up; ages at breast or ovarian cancer diagnoses; and age or date at bilateral prophylactic mastectomy and oophorectomy.

Recently, clinical NGS tests using targeted gene panels or whole exome sequencing (WES) have been used to identify pathogenic sequence mutations including single nucleotide variations (SNVs) and small insertion-deletions (indels) in both adult6,7,8 and pediatric cancer studies8,9,10.

These structures can be significantly disrupted by mutations including Single Nucleotide Polymorphisms (SNPs) [ 11, 12].

Compared with the " CYP5005A7P" sequence, the EST of the cDNA transcript has several site mutations including one nucleotide transition (A to G) within the in-frame stop codon found in the genomic sequence, and thus can be read through.

We performed an exome-wide study of somatic mutations, including single nucleotide variants (SNVs) and short insertions and deletions (indels), from 100 colon adenocarcinoma patients obtained from The Cancer Genome Atlas (TCGA) project [ 16].