Sentence examples for mutations in tissue from inspiring English sources

More recently the gene has been reported to show a variety of mutations both deletions and point mutations in tissue samples from patients with melanoma [17].

The presence and extent of LOH mutations in tissue was correlated to its histological class.

Recent studies have included a comprehensive analysis of mtDNA mutations in tissue of the atherosclerotic vascular wall.

8 11 To explore whether overexpression of STK33 proteins is associated with Ras mutations in HCC, we detected Ras mutations in tissue samples of 251 patients with HCC.

In conclusion, the one-step procedure discribed may be a useful clinical tool for analysing Ki-ras point mutations in tissue and plasmas samples.

Although the bioinformatics pipeline used, coupled with visual inspection of the data, allowed us to evaluate the results, it was not optimised or validated for routine screening for BRCA mutations in tissue samples.

MAP provides a general tool for monitoring ultra-rare mutations in tissues and blood.

Stem cells are expected to play a major role in strategies to minimize the accumulation of mutations in tissues.

In addition, researchers have found RNA-Seq to be a powerful tool for the detection of differentially expressed genes, rare transcripts, novel isoforms, and mutations in tissues [ 7– 10].

Cancer predisposition in such carriers is due not only to effects of these mutations in tissues with an elevated cancer risk, but also in organs that control the menstrual cycle, which influences such tissues.

In conclusion, we found that neoplasms induced by Ras V12/scrib mutations in tissues of neural ectodermal and mesodermal origins behaved similarly in every manner examined: cell cycle checkpoints, cellular morphology, apoptosis, aneuploidy and response to Taxol.