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The majority of TP53 mutated tumors harbor missense mutations in this gene, correlated with p53 accumulation.
Mutations in this gene cause an accumulation of nonfunctional proteins.
Her mother and father carried different mutations in this gene.
None of the designed single residue mutations in this study affected the P particle formation.
Mutations in this gene have also been detected in sporadic parathyroid carcinoma [10].
Mutations in this gene are responsible for germline mutations that can induce cancer.
Mutations in this gene can cause variable phenotypes with different patterns of inheritance.
Therefore, the mutations in this region may have affected the direct interaction of Psu with Rho.
However, we did not detect mutations in this gene in a family with DFNB13 hearing loss.
Mutations in this region affect BRCA1′s ability to repair DNA and also hinder its ability as a tumor suppressor.
Mutations in this gene result in clinical heterogeneity, including hemiplegic migraine, episodic ataxia, or progressive chronic conditions.
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