Sentence examples for mutations in terms of from inspiring English sources

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(B ) Identity and fate of the mutated bases (as percentages of the total mutations) in terms of top strand sequence induced by repair that either restored lesions to C/G (left quadrants) or converted T/G to T/A (right quadrants, gray box) for top strand (upper two quadrants) and bottom strand (lower two quadrants) lesions on FM1.

In this case, the top strand serves as the repair template, but because we show all the mutations in terms of the top strand sequence the final mutational outcome is basically the complement of the results generated from the repair of top strand lesions.

Here, we evaluate the most widely-used methods for the detection of on-target and off-target mutations in terms of workflow, sensitivity, strengths and weaknesses.

The effects of both Q212P and R220K mutations in terms of unstructured C-terminal parts of proteins are comparable (Figures 7A and B).

This highlights two salient points: (i) If a simple genetic disease such as CF can have more than 1000 functional deleterious variants, are there reasons to believe that the number and spectrum of functional mutations (in terms of non-synonymous substitutions, stop-mutations, deletions, splice mutations etc.,) should be different for genes with more subtle effects on complex diseases?

We quantified the effects of mutations in terms of site-specific amino-acid 'preferences'preferences

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Thus, the significance of this mutation in terms of pathogenicity needs to be verified.

These data indicate that the PNPLA3 148M is a loss-of-function mutation in terms of regulation of lipid droplet metabolism in human HSCs.

Since 2004, the predictive value of somatic KRAS mutation, in terms of resistance to anti-EGFR mAbs, has been established by numerous studies.

Further, it will better define the mutation in terms of its effects on primary cell wall elongation and early secondary cell wall synthesis.

The kinetic advantage afforded by the Q115E mutation in terms of TCR/pMHCI binding is likely to enhance antigenicity per se.

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