Sentence examples for mutations in strains from inspiring English sources

However, it would be impractical, because it would eliminate many important drug resistance mutations in strains likely to be transmitted from treated individuals.

In an attempt to shed light on this, we designed and constructed mucA alleles with different SSR compositions by site directed mutagenesis, and then analyzed the emergence frequency of mucoid variants and the spectrum of mucA mutations in strains carrying the different mucA alleles.

Mutations in strains Newman and COL have been described [ 40- 42], and both strains are members of clonal complex 8 and readily produce endocarditis in rats.

Through genome resequencing and functional analysis, identification of precise mutations in strains with altered phenotypes will add insight into specific gene functions and guide further metabolic engineering efforts.

Continued exposure to a drug seems to impose constraints on evolution that facilitate the acquisition of compensatory mutations in strains that are already resistant [ 36, 50].

Again, this study identified rpoB mutations in strains that were better adapted to carbon limitation, n-butanol, osmotic and acid stress.

Figure  5a shows the time the mutations in strain F emerged.

The number of mutations in strain A was significantly higher than other strains (Additional file 9: Table S3).

Some of the "mutations in strain" might be more accurately described as variants (see discussion of polymorphic pseudogenes, below).

Based on the raw sequence data, we identified 44532 and 44030 mutations in strain P5 and strain P24, respectively, in comparison to the reference strain.

The discrepancy (4 point mutations in strain A) was checked by Sanger sequencing, and it was confirmed that 3 were true positives and the other a false positive.