Sentence examples for mutations in specimens from inspiring English sources

In the future, it is anticipated that a newer version of the TaqMan® detection method that is currently under development will further improve the sensitivities of individual assays such that they will all reliably detect mutations in specimens containing as little as 1% tumor cells.

Antiviral resistance mutations in specimens from patients with H7N9 infection have been reported recently.

Epithelial cells containing the TP53 mutation in specimens PO3 and PO67 also displayed loss of heterozygosity (LOH) of the wild-type BRCA1 or BRCA2 alleles, respectively (Figure 1D; Supplemental Table S1).

Optimization of OLA probes to accommodate polymorphisms in regional HIV variants improved OLA performance, and comparison to the USA results showed successful implementation of the OLA in Zimbabwe for detection of NVP resistance mutations in DBS specimens.

It is not known whether pre-operative identification of BRAF mutations in cytologic specimens should alter surgical management.

Similarly Menegon et al. [39] found seven mutations in 71 specimens.

EGFR and K-Ras mutations in 60 specimens of LCLC were detected by direct DNA sequencing.

Previous studies detected no KRAS mutations in NPC specimens or cell lines [ 29, 40].

Sequencing of cDNA showed P53 missense mutations in 15 specimens and nonsense mutation in one case of 23 analyzed CC.

In conclusion, we demonstrate that the sensitive detection of single molecule mutations in clinical specimens is feasible by SP-PCR.

Logistic regression analysis revealed that EGFR mutations in cytology specimens represented an independent predictor of the gefitinib response.