Sentence examples for mutations in proportion from inspiring English sources

Although the difference between light and heavy smokers was marginal, there was an increasing trend of p53 mutations in proportion to the amount of tobacco smoking (OR, 1.0; 95% CI, 1.0 1.1; P = 0.04, per 5 pack-years).

Typically, in genetic diseases caused by mutations in high proportion of DNA, sensitivity of diagnostic assays is not a critical factor for SNP detection.

Our hypothesis is that we will be able to identify the disease-causing mutations in a proportion of these participants.

The role of CDKN2A on melanogenesis is mainly explained by the presence of germline mutations in a proportion of familial melanoma [ 7].

Even a very slight advantage is sufficient to cause new beneficial mutations to increase in proportion over the span of many generations.

Rather, beneficial mutations simply increase in proportion from one generation to the next because, by definition, they happen to contribute to the survival and reproductive success of the organisms carrying them.

As a result, the driver score of a mutation (gene) is in proportion to the total votes the mutation (gene) received and the total votes received by the patient determine the patient score.

Our findings indicate that routine tumor genotyping is helpful in identifying low-frequency mutations, such as GNAS, that may correlate with a specific morphological phenotype and also reveal multiplicity of concurrent mutations in a significant proportion of CRC that may have significant implications for clinical trial design and personalized therapy.

Research on Beijing strains from Germany and Russia showed mutations in a high proportion of the genes rpoB S531L and embB306.

A drawback of this regimen is the selection of resistance mutations in a large proportion of exposed women and their infected infants [ 2].

We present data on a large cohort of women identified as carriers or presumed carriers of BRCA1 and BRCA2 mutations in a large proportion of the UK population.