Sentence examples for mutations in particular from inspiring English sources

MPL mutations, in particular W515L, W515K, W515A, S505N and G509C, were tested by direct sequencing of exon 10.

While standard testing could not find mutations in particular genes in 10 of the 22 patients, the experimental procedure let researchers identify the abnormal genes in all the patients.

The identification of single-base mutations in particular genes plays an increasingly important role in medical diagnosis and prognosis of genetic-based diseases.

Incomplete repair of DPX can lead to the formation of mutations, in particular chromosome mutations and micronuclei (MN) in proliferating cells.

They can identify mutations in particular genes, and they can monitor the activity of lots of genes at the same time showing a doctor which genes in a tumour are busier than they should be, and which are less busy.

The field of premature aging has garnered immense interest also because of the emerging number of premature aging disorders observed in humans, with a significant proportion of the syndromes originating from mutations in particular genes.

One mutation in particular spread from fewer than 10percentt of the Han Chinese to nearly 90percentt of all Tibetans.

In the age of personalised medicines, antisense oligonucleotides can sometimes be designed to target and bypass or overcome a patient's genetic mutation, in particular those lesions that compromise normal pre-mRNA processing.

The inclusion of the lpr mutation in particular enhances disease severity, by triggering lymphoproliferative pathology.

One MyD88 mutation in particular, in which Leu is changed to a proline residue, accounts for approximately a third of all cases of DLBCL [ 20].

The effect of genetic mutation in particular TFBSs on the methylation state of CpGis has recently been refined by Lienert et al. [ 27].