Sentence examples for mutations in parallel from inspiring English sources

This C-terminal movement was facilitated and hindered by specific mutations in parallel with experimentally observed facilitation and inhibition of fusion.

Recently, high-throughput sequencing has been coupled to assays of protein activity, enabling the analysis of large numbers of mutations in parallel.

Appropriate emphasis has been placed on the presence of the JAK2 V617F and similar activating mutations in parallel with recent clinical practice.

The advantages offered by the MassARRAY system include high-throughput screening for many hot-spot mutations in parallel, use of minimal DNA isolated from formalin-fixed paraffin-embedded tissues, ability to detect coexisting multiple mutations, and cost and time effectiveness.

The presence of polymorphic elements sharing specific mutations is indicative of the activity of a secondary source element, as polymorphic elements have recently retrotransposed and are therefore unlikely to have accumulated such mutations in parallel.

Although several empirical studies have provided examples in which similar phenotypes are produced by the repeated selection of the same pool of standing variation (Barrett and Schluter 2008; Nadeau and Jiggins 2010), the relative importance of standing variation and new mutations in parallel phenotypic evolution is as yet poorly understood (Elmer and Meyer 2011; Conte et al. 2012).

In this model, the range of possible epitypes for a sequence would evolve by gene duplication and mutation in parallel with genotype [ 19, 51].

5 In the blood samples from those patients with the T790M mutation, the amount of T790M and EGFR-sensitizing mutations increased in parallel for some but not all patients.

Mutations in a parallel pathway, the FAT signalling pathway, also result in hair cell defects, and VANGL2 and FAT4 genetically interact (Ezan and Montcouquiol, 2013; Saburi et al., 2008; Sienknecht et al., 2014).

They wrote experimental proposals to address their rationales and hypotheses for the "mutations"; conducted experiments in parallel, according to both standard and mutated protocols; and then compared and analyzed results to write individual lab reports.

Mutant and sibling pools representing up to 24 different mutations were tested in parallel.