Sentence examples for mutations in mutation from inspiring English sources

The non-random clustering mutations in mutation showers should provide more definitive data for the occurrence of chronocoordinate mutations in human cancers.

As mutations in mutation accumulation experiments are strand agnostic, that is, they do not distinguish between the coding and template strand nucleotides, we cannot distinguish between the mutations NNC → NNG and NNG → NNC nor NNA → NNT and NNT → NNA.

This point is underscored by the fact that mutation in mutation hotspots often leads to recurrent genetic disease [ 186, 187].

Our analysis also suggests substantial variation in mutation rates even among mutations involving the same nucleotide changes.

In heterozygous mutations, the mutation's VAF is expected to be half of the clone size if the mutation occurs in all of the clone's cells.

Other mutations include nonsense mutations, missense mutations and in-frame deletion (Everett, 2011).

Such reversion may occur as a result of back-mutation of attenuating mutations, compensatory mutations elsewhere in the genome, or as discussed in the next section, recombination.

Analysis of the p53 exon 5 mutation spectrum in mutation databases for lung cancer reveals frequent GC > AT transitions, several of which occur at non-CpG sequences.

Of the five individuals, four were found to have somatic EPAS1 mutations, all of which resulted in mutation of either amino acid residue A530 or P531 (P531R (x2), P531R, A530P 45.

MUDPAC requires two input data sets: mutation data in mutation annotation format (.maf), and pathway data with topology information.

Of these 51 mutations, 38 mutations clustered in exon-9 and the remaining 13 exon 20 (Table 1).