Sentence examples for mutations in mixed from inspiring English sources

Second, direct sequencing may be not able to provide satisfactory results for detection of EGFR mutations in mixed samples of mutated and wild DNA.

Analysis of SNP mutations in mixed bacterial genotypes was as described by Barrick et al. [24], [52].

HRM analysis is able to detect mutations in mixed PCR fragments containing other SNPs (among the homoeologous loci).

However, accelerated accumulation of (expanded) mutations in mixed scenario can only be explained by generation of de novo mutations at older ages.

A higher frequency of PIK3CA mutations in mixed DCIS (8 out of 33, 24%%) than in pure DCIS (0 out of 31) has been reported in a specific group of high-grade, estrogen receptor-positive, HER2-negative DCIS cases [ 72].

The higher prevalence of the A908G mutation in mixed lobular/ductal tumors might explain in part the stronger association of the mutation with tumor grade II rather than grade III, because breast tumors with a lobular component tend to be of lower grade than non-lobular tumors.

This finding indicates that the frequency of MSI in young patients with rectal cancer is considerably lower than the 17 58% MSI tumors and 20 40% HNPCC-causing mutations reported in mixed series of colorectal cancers from young patients [ 5- 14, 18] 18].

We demonstrate that High Resolution Melting (HRM) analysis can be used in mutation scans in mixed PCR amplicons containing three homoeologous gene fragments.

These tools are designed to extract allele frequencies and thus are also well adapted for the detection of mutation frequencies in mixed populations.

We did not identify mutations in the single mixed hepatocellular-cholangiocarcinoma evaluated.

Various mutations were detected on the KIT gene: deletions, point mutations or mixed mutations in exon 11 (core=0; n=13), or alternately insertion in exon 9 (AY 502 503 duplication) or wt profile, that is no mutation (code=1; n=7).